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Your GenAI Antibody Discovery Partner

Your GenAI Antibody Discovery Partner

Converge Bio is accelerating drug development through GenAI-powered innovations in discovery, molecule design, and manufacturing, creating tomorrow's therapies today.

Converge Bio is accelerating drug development through GenAI-powered innovations in discovery, molecule design, and manufacturing, creating tomorrow's therapies today.

Generate

Predict

Explain

Predict binding & developability

Generate

Predict

Explain

Predict binding

01

01

Generate diverse antibody candidates in silico

Optimized antibody candidates, generated with unprecedented speed and precision through AI-driven molecule design. Define your target and optional constraints, and ConvergeAB uses computational molecule design and affinity maturation to design molecule variants, rapidly producing diverse sequences ranked for binding affinity, structural stability, and functional relevance.

Optimized antibody candidates, generated with unprecedented speed and precision through AI-driven molecule design. Define your target and optional constraints, and ConvergeAB uses computational molecule design and affinity maturation to design molecule variants, rapidly producing diverse sequences ranked for binding affinity, structural stability, and functional relevance.

02

02

Better leads,
fewer cycles

Optimize affinity, stability, solubility, immunogenicity, and expression in a single AI-driven molecule design pass. Each lead is derived from millions of in silico designs, ranked and filtered to maximize success and cut lab iterations.

Optimize affinity, stability, solubility, immunogenicity, and expression in a single AI-driven molecule design pass. Each lead is derived from millions of in silico designs, ranked and filtered to maximize success and cut lab iterations.

03

03

Prioritize high-performing candidates before entering the lab

ConvergeAB screens millions of antibody sequences per target using AI-driven molecule design, scoring each for affinity, developability, epitope specificity, humanization, and structural fit. Clear scores and visual outputs enable confident selection, accelerating discovery and reducing experimental burden.

ConvergeAB screens millions of antibody sequences per target using AI-driven molecule design, scoring each for affinity, developability, epitope specificity, humanization, and structural fit. Clear scores and visual outputs enable confident selection, accelerating discovery and reducing experimental burden.

04

04

Generate, optimize and screen - all in one single platform

Each candidate includes rich predictive profiles - affinity, stability, solubility, immunogenicity, and docking-based structural fit - powered by AI-driven molecule design. Review key metrics, explore 3D visualizations, and export top sequences for synthesis, whether you validate in-house or with a CRO, moving forward with confidence and clarity.

Each candidate includes rich predictive profiles - affinity, stability, solubility, immunogenicity, and docking-based structural fit - powered by AI-driven molecule design. Review key metrics, explore 3D visualizations, and export top sequences for synthesis, whether you validate in-house or with a CRO, moving forward with confidence and clarity.

How it works

How it works

ConvergeAB™ is trained on over 1 trillion natural protein tokens, including 7 million antibody sequences, 3 million antibody–antigen pairs, and 10,000 developability measurements. This foundation enables affinity maturation, developability optimization, humanization, patent escape and IP expansion, and candidate screening across IgG, ScFv, and VHH (Beta) formats.

Input

Input

You provide the biological elements: a mandatory protein sequence defining the final product, and optional regulatory regions. The promoter controls gene expression strength, while the 5’ and 3’ UTRs influence mRNA stability, translation efficiency, and overall protein yield, all of which can be optimized.

Input

You provide the biological elements: a mandatory protein sequence defining the final product, and optional regulatory regions. The promoter controls gene expression strength, while the 5’ and 3’ UTRs influence mRNA stability, translation efficiency, and overall protein yield, all of which can be optimized.

2nd

Predictors

Predictors

Each predictor scores generated antibodies on key drug-development properties: correct heavy/light chain pairing, binding strength, off-target risk, cellular expression, solubility, thermostability, aggregation risk, and self-association, ensuring selected candidates are potent, stable, and manufacturable.

Predictors

Each predictor scores generated antibodies on key drug-development properties: correct heavy/light chain pairing, binding strength, off-target risk, cellular expression, solubility, thermostability, aggregation risk, and self-association, ensuring selected candidates are potent, stable, and manufacturable.

2nd

Output

Output

After generating and scoring many designs, the system selects a small set of high-confidence antibody candidates that bind strongly, demonstrate developability and manufacturability, and carry lower risk of failure—ready for experimental validation in the lab.

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Start designing
better antibodies

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Start designing
better antibodies